針山孝彦

HARIYAMA Takahiko

浜松医科大学医学部特命研究教授
ナノスーツ代表取締役

プロフィール

所属学会
比較生理生化学会
動物学会
応用動物昆虫学会他

専門
光生物学・バイオミメティクス・ナノスーツ開発他

経歴を踏まえた研究・開発のバックグラウンド
生理学を中心に生物全体を見るようにしている。15年ほど前からバイオミメティクス研究を始め、その中でナノスーツ法を発明

本プロジェクトへの寄与
生理学的視点、技術提供としてナノスーツ法および高感度計測

著書・論文
Takahiko Hariyama, Yasuharu Takaku, Hideya Kawasaki, Masatsugu Shimomura, Chiyo Senoh, Yumi Yamahama, Atsushi Hozumi, Satoru Ito, Naoto Matsuda, Satoshi Yamada, Toshiya Itoh, Miki Haseyama, Takahiro Ogawa, Naoki Mori, Shuhei So, Hidefumi Mitsuno, Masahiro Ohara, Shuhei Nomura, Masao Hirasaka　（2021）Microscopy and biomimetics: the NanoSuit® method and image retrieval platform. Microscopy DOI:10.1093/jmicro/dfab042

Hideya Kawasaki, Hiromi Suzuki, Masato Maekawa, Takahiko Hariyama (2021) Combination of the NanoSuit method and gold/platinum particle-based lateral flow assay for quantitative and highly sensitive diagnosis using a desktop scanning electron microscope, Journal of Pharmaceutical and Biomedical Analysis, DOI: 10.1016/j.jpba.2021.113924

Sayuri Takehara, Yasuharu Takaku, Masatsugu Shimomura, Takahiko Hariyama (2020) Imaging dataset of fresh hydrous plants obtained by field-emission scanning electron microscopy conducted using a protective NanoSuit, PLoS ONE, DOI: 10.1371/journal.pone.0232992

Yasuharu Takaku, Sayuri Takehara, Chiaki Suzuki, Hiroshi Suzuki, Masatsugu Shimomura, Takahiko Hariyama (2020) In situ elemental analyses of living biological specimens using 'NanoSuit' and EDS methods in FE-SEM, Scientific Reports, DOI: 10.1038/s41598-020-71523-8

Takahiko Hariyama, Yasuharu Takaku, Chiaki Suzuki, Sayuri Takehara, Satoshi Hirakawa, Hiroshi Suzuki, and Hideya Kawasaki (2019) Living Organisms under an Electron Microscope: the NanoSuit®, Journal of Photopolymer Science and Technology, DOI: 10.2494/photopolymer.32.287

Takahiko Hariyama, Kana Sakaida, Haruko Matsumoto, Takami Tsutsui, Hiroshi Suzuki, Hideya Kawasaki, Masatsugu Shimomura, Yasuharu Takaku (2017) A Thin Polymer Membrane ‘NanoSuit’ Allows Living Organisms to Survive in the Harsh Conditions of Electron Microscopy, Proceedings of SPIE, DOI: 10.1117/12.2260812

Yasuharu Takaku, Hiroshi Suzuki, Hideya Kawasaki, Isao Ohta, Daisuke Ishii, Satoshi Hirakawa, Takami Tsutsui, Haruko Matsumoto, Sayuri Takehara, Chinatsu Nakane, Kana Sakaida, Chiaki Suzuki, Yoshinori Muranaka, Hirotoshi Kikuchi, Hiroyuki Konno, Masatsugu Shimomura and Takahiko Hariyama (2017) A modified `NanoSuit®’ preserves wet samples in high vacuum: direct observations on cells and tissues in field-emission scanning electron microscopy, Royal Society Open Science, DOI: 10.1098/rsos.160887

Yasuharu Takaku, Hiroshi Suzuki, Isao Ohta, Daisuke Ishii, Yoshinori Muranaka, Masatsugu Shimomura, and Takahiko Hariyama (2013) A thin polymer membrane, nano-suit, enhancing survival across the continuum between air and high vacuum, PNAS, DOI: 10.1073/pnas.1221341110

Website
NanoSuit株式会社
 光尖端医学教育研究センターナノスーツ開発研究部
 浜松医科大学医学部生物学針山研究室
 TEDxHamamatsu 2016